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Lysozyme is a natural antimicrobial agent obtained from liquid egg white in the hydrochloride form for food use. Lysozyme can attack cell wall polysaccharides of different bacterial species, especially Gram positive bacteria, leading to rupture of the cell wall and killing of the microorganisms. It is also a raw material for pharmaceutical industry.
As a food additive, it has E numer E1105.
Structural unit and Molecular structure
Lysozyme is a polypeptide obtained from hen's egg whites consisting of 129 amino acids; it is usually obtained in the hydrochloride form for food use and it possesses enzymatic activity. Molecular weight: 14000 g/mol
Manufacture and Quality Control of Lysozyme
egg white -ADSORPTION - DESORPTION - SEPERATION & CONCENTRATION - SPRAY DRYING -CONTROLS ON THE FINAL PRODUCT -PACKING
Regarding Quality Control points during and after production of Lysozyme, note that RADA brand Lysozyme meets with FCC IV and USP, and other international food additive standards. Products are produced in accordance with CGMP/HACCP /ISO requirements. We have the certification of ISO9001:2000, ISO22000 (HACCP), HALAL and KOSHER.
Properties and Application of Lysozyme
Microbiologic Character: Lysozyme can solubilize the membrane of the most bacteria cell walls by hydrolyzing the bonds between NAG subunits of the glucoproteins of the bacterial cell walls, so as to kill the cells. It is especially effective on Gram(+), bacillus subtilis, and other spore-forming bacillus, etc.
Solubility and stability:
- have no solubility in acetone and ethanol solutions, completely soluble in salt solution.
- Maintains its activity at 55oC, or at 62,5oC for 30 min. in water solution, or at 62,5oC for 20min. in 20% ethanol solution.
Antimicrobial property:
Lysozym; is used in cheese production to prevent "late blowing". This phenomenon is caused by the growth of Clostridium tyrobutyricum, a contaminant present in milk used for cheese production. Lysozym; can attack cell wall polysaccharides of different bacterial species, especially Gram positive bacteria, leading to rupture of the cell wall and killing of the microorganism.
Lysozym; is known as an effective immunological agent. It is used in human therapy for the treatment of viral and bacterial infections. Lysozym has analgesic properties and has been used as a potentiating agent in antibiotic therapy. Lysozym is used in the prophylaxis and therapy of leukopenia induced by antiblastic and ionizing radiation. EDTA-tris- lysozym solutions are effective in the treatment of coliform infections of the bladder in humans. The anti-inflammatory action of lysozym consists in the neutralization of acid substances released in the inflammatory process. Stipulation of phagocytosis by lysozym favours wound healing and regression of degenerative and necrotic processes. Lysozym-mediated decrease of mast cell degranulation leads to reduction of histamine release and a subsequent anti-oedema effect.
Application: Lysozyme can be used in a variety of foods and pharmaceuticals:
- Lysozyme has been used to preserve fresh fruits and vegetables, seafoods, meats and sausages, vegetable and fruit based preserves, noodle-type deep frozen prepared foods, prepared ready to eat salads.
- It can be used to prevent the late blowing in hard and semi-hard cheese with long ripening.
- Lysozyme added to infant-feeding formulas makes them more closely resemble human milk. It can ensure the bifidobacterium propagation in baby’s intestines.
- Lysozyme has been used clinically in the treatment of periodontitis, administered in chewing gum, and implemented to prevent tooth decay.
- It has also been administered to patients suffering from cancer for its analgesic effect and has been used as a potentiating agent in antibiotic therapy.
Presentation Units and Shelf Life
Product Name
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Packaging Unit
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Packaging Type
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Shelf Life
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Storage Conditions
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Lysozyme
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1.000 gr.
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High Density Food Grade plastic bottle
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9 months
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Sealed and stored in dry conditions, at Room Temperature.
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Please contact us at 0 232 463 1740 to be provided for the documents you might need such as Halal, Kosher, HACCP, NON GMO Statement, Allergen Statement, MSDS, Specification Sheet, Certificate of Analysis, Health Certificate, ISO 9001:2000 and ISO 22000:2005.